パパヤ(Carica papaya L)の多食に因する柑皮症の1例

A case of aurantiasis cutis caused by having taken much papaya

岡谷, 昇

Okaya, Noboru

In 1896, Baelz described, for the first time in Japan, concerning the aurantiasiscutis caused by taking a lot of mikan. Later in Hokkaido, Drs. Ishikawa and Okada reported some cases of the yellow coloured skin after taking much pumpkin. In November of 1937, the author who has investigated during about the 16 years in the islands of Paran and Saipan observed for the first time a case caused by taking papayas which is the common name of the fruit of caria papaya planted in nearly all the islands of the tropical territories;- A japanese girl aged 16, taking the advice of a certain doctor who had examined her under the diagnosis of beriberi, ate two papayas as large as a baby head every day in October last. At the begining of November, she happened to notice her hands and feet growing yellow. Gmelin's test for bile pigments in her urine was examined for repeatedly but always was negative not only on the mucous membrane of the eyes and throat, but on other parts of the skin of her face, body and extremities, were scarcely yellow coloured, except the palm of the hands and the soles of the feet. The yellow pigment remained there for over 2 months after she had ceased taking papayas, and neither pains nor itching took place. The hard parts of the palms and soles were remarkably coloured with yellow pigment, especially when finger-pressure was put on them. According to the investigation of Dr. Kariyone the pigment which is contained within papayas is the Kryptoxanthin (C40H56O), a kind of carotinoid. Therefore the author believes that the cause of this aurantiasis cutis is due to having taken too much papaya. (The Author's abstract)

https://opac.ll.chiba-u.jp/da/curator/900050241/

https://opac.ll.chiba-u.jp/da/curator/900050241/1602011.pdf

千葉医学会

学術雑誌論文

0009-3459

AN00142206

千葉醫學會雜誌

16

2

21

22

1938-02-28

千葉医学 (ONLINE ISSN 2433-4243)