Osteophyte formation at the posterior notch of the femur serves as an early sign of osteoarthritic change of the knee joint

[SUMMARY] We previously reported that osteophytes formed at the posterior condylar notch of the femur could serve as a predictive imaging biomarker for osteoarthritis of the knee joint（KOA）development using magnetic resonance imaging（MRI）. Considering the location in the knee joint, we named the osteophyte as hidden osteophyte formation on plain x-ray（HOPOX）. To apply the findings to general clinical usage, x-rays that are less costly than MRI are a preferred imaging modality. In this study, we examined the feasibility of using the x-ray tunnel view to detect HOPOX. First, the diagnostic ability of the tunnel view was examined in 30 cases using computed tomography（CT）as a standard reference. Then, in a longitudinal study, the timing of HOPOX formation was examined retrospectively with a radiographic follow-up of 28 meniscectomized knees. The tunnel view showed greater diagnostic ability ; the sensitivity, specificity, positive predictive value, and negative predictive value were 0.73, 0.93, 0.92, and 0.78 respectively. The longitudinal study revealed that HOPOX was the earliest osteophyte in those cases in which osteophytes formed. In conclusion, the x-ray tunnel view was effective in detecting HOPOX, thus feasible way to predict early KOA.

https://opac.ll.chiba-u.jp/da/curator/107793/

https://opac.ll.chiba-u.jp/da/curator/107793/S03035476-96E-1-P21.pdf

The Chiba Medical Society

千葉医学会

学術雑誌論文

AN00142148

Chiba medical journal

96E

1

21

26

2019-02-10

10.20776/S03035476-96E-1-P21

publisher

Chiba Medical Journal (ONLINE ISSN 2433-4235)