新美, 仁男

小島, 博之

沼田, 朋子

冨板, 美奈子

KOHNO, Yoichi

ニイミ, ヒロオ

NIIMI, Hiroo

コジマ, ヒロユキ

KOJIMA, Hiroyuki

ヌマタ, トモコ

NUMATA, Tomoko

トミタ, ミナコ

TOMIITA, Minako

食物除去試験

食物誘発試験

卵アレルギー

アナフィラキシーショック

Adverse food reactions, a generic term referring to any untoward reaction after the ingestion of a food, are secondary to food allergy or food intolerance. Food allergy is the result of an abnormal immunologic response to food proteins, whereas a food intolerance is the result of nonimmunologic mechanisms. The clinical signs and symptoms of food allergy are due to a variety of syndromes, including urticaria, atopic dermatitis, angioedema, bronchial asthma, rhinoconjunctivitis, gastrointestinal allergy, and so on. Diagnosis is based on clinical history, positive skin tests, and elevated levels of allergen-specific IgE antibodies. Finally, diagnosis is established by complete elimination of the suspected food allergen with resolution of symptoms and oral food challenges. Once food allergy is diagnosed, the only proven therapy is avoidance of the specific food allergen. In the vast majority of individuals, tolerance develops to the food antigen. In contrast, some patients with food allergy are sensitized against inhalant allergens such as house dust mites and subsequently suffer from bronchial asthma even though they overcome their food hypersensitivity.