男子不妊症

内精静脈造影

プロスタグランディン

原著

The purpose of this study was to clarify whether varicocele was a cause of male infertility or not, and to investigate the mechanism for the deleterious effect of vasicocele on speramtogenesis. The results obtained were as follows. 1) Sperm motility of varicocele patients was significantly lower than that of idiopathic infertility. 2) Semen quality and pregnancy rate improved after varicocelectomy. 3) Although no difference in serum cortisol and serotonin levels was observed between the internal spermatic and peripheral veins in varicocele patients, prostaglandin (PG) E and PGE levels were significantly higher in internal spermatic vein blood than in peripheral vein blood. 4) Improvement of semen quality and pregnancy rate was better in patients whose gonadal venography showed reflux into the left kidney than in patients who had no reflux. These results suggest that var